Mohammad-Reza Ardalan
1*1 Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: *Corresponding author: Prof. Mohammad-Reza Ardalan, Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. , Email:
ardalan34@yahoo.comcom
Abstract
Implication for health policy/practice/research/medical education:Congo red negative nodular deposition of an amorphous, eosinophilic material is the most common pathologic finding in light chain deposition disease in light microscopy. The nodules are a mixture of light chain and mesangial protein and the picture is reminiscent of diabetic nephropathy. Immunoflurescent microscopy usually demonstrates the presence of monotypic kappa light chain. It seems that serum creatinine level greater than 4 mg/dl is a poor prognosis sign for future progress to end stage renal disease in this disease. Therefore, early diagnosis is important.