eISSN: 2345-2781  
J Renal Inj Prev. 2015;4(3).
doi: 10.12861/jrip.2015.15
PMID: 26468478
PMCID: PMC4594217

Original Article

Effect of sour tea (Lipicom) pill versus captopril on the treatment of hypertension

Ali-Reza Soleimani 1, Hossein Akbari 2, Saeid Soleimani 3, Seyed Seifollah Beladi Mousavi 4, Mohamad-Reza Tamadon 5 *

1 Department of Internal Diseases, Kashan University of Medical Sciences, Kashan, Iran
2 Department of Statistics, Kashan University of Medical Sciences, Kashan, Iran
3 Department of Internal Diseases, Kashan University of Medical Sciences, Kashan, Iran
4 Chronic Renal Failure Research Center, Ahvaz Junishapur University of Medical Sciences, Ahvaz, Iran
5 Department of Internal Medicine, Semnan University of Medical Sciences, Semnan, Iran
*Corresponding author: Mohamad-Reza Tamadon, Email: mrt_tamadon@yahoo.com

Abstract

Introduction: Herbal medicines are traditionally prescribed to manage blood pressure.

Objectives: We aimed to evaluate effect of sour tea pill containing the herb’s extract versus captopril on the treatment of hypertension.

Patients and Methods: In our crossover clinical trial 20 patients were enrolled in the study and advised for life style modification then the participants were randomly divided into 2 groups. Sour tea pills was prescribed at a dose of 500 mg and captopril at a dose of 12.5 mg twice daily. In order to improve precision and final measurement, ambulatory blood pressure monitoring (ABPM) was performed both prior and after measuring the hypertension in 2 successive visits. After 6 weeks of therapy, the methods changed and 6 weeks later ABPM was performed three times (baseline, at end of the 6th and 12th week). The 2 groups were merged together before data analysis.

Results: Of the 20 patients, 13 (65%) were male and 7 (35%) were female. No significant difference of sex, age, and job was detected between 2 groups (P ≥ 0.05). Mean decreasing in systolic blood pressure was 7.75 ± 8.3 and 13.3 ± 16.1 mm Hg in the captopril and sour tea groups, respectively. Also, mean decline in diastolic blood pressure decreases was 2.15 ± 4.14 and 5.8 ± 7.8 mm Hg for captopril and sour tea groups, respectively. No side effect was observed in the sour tea pill group in the study.

Conclusion: According to the effect of sour tea pill on decreasing blood pressure, without giving priority over captopril, sour tea pill containing the herb’s extract can be prescribed as an adjuvant therapy for lowering the prescribed dosage of captopril.

Implication for health policy/practice/research/medical education:

In this study we indicated the antihypertensive effect of sour tea, while its priority over captopril is not proved. It could be administrated as a supportive therapy to minimize the dose of the drug used.

Please cite this paper as: Soleimani AR, Akbari H, Soleimani S, Beladi Mousavi S, Tamadon MR. Effect of sour tea (Lipicom) pill versus captopril on the treatment of hypertension. J Renal Inj Prev. 2015; 4(3): 73-79. DOI: 10.12861/jrip.2015.15

First name
 
Last name
 
Email address
 
Comments
 
Security code