eISSN: 2345-2781  

First published online: 24 Oct 2016
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Abstract Page Views: 588
PDF Downloads: 364
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J Renal Inj Prev. 2017;6(1):16-17.
doi: 10.15171/jrip.2017.03
PMID: 28487866
PMCID: PMC5414513
Scopus id: 85019355997

Authors' Reply

Updates on the risk factors of acute kidney injury after transcatheter aortic valve replacement

Wisit Cheungpasitporn 1, Charat Thongprayoon 2, Kianoush Kashani 1,3 *

1 Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA
2 Department of Internal Medicine, Bassett Medical Center, Cooperstown, NY, USA
3 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA
*Corresponding author: Kianoush Kashani, Email: kashani.kianoush@mayo.edu

Implication for health policy/practice/research/medical education:

In our recent updated studies, we found a significant association between periprocedural blood transfusion and acute kidney injury (AKI) following transcatheter aortic valve replacement (TAVR) with an overall 1.95-fold increased the risk of AKI. We also demonstrated that a transapical approach was significantly associated with increased AKI risk compared with a transfemoral approach. Nevertheless, the TAVR approach did not affect severe renal outcomes or long-term renal function. In addition, our meta-analysis demonstrated no significant association between contrast media volume and risk of AKI after TAVR. Thus, the dose of contrast media likely does not play a significant role in the pathogenesis of TAVR-related AKI. Growing knowledge of these risk factors of TAVR on kidney function will help improve preventive measures to improve patients’ outcomes.

Please cite this paper as: Cheungpasitporn W, Thongprayoon C, Kashani K. Updates on the risk factors of acute kidney injury after transcatheter aortic valve replacement. J Renal Inj Prev. 2017;6(1):16-17. DOI: 10.15171/jrip.2017.03

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