eISSN: 2345-2781  



First published online: 25 Dec 2016
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Abstract Page Views: 126
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. 2017;6(2):137-141.
doi: 10.15171/jrip.2017.27
PMID: 28497091
PMCID: PMC5423282

Original Article

Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers

Niloufar Zadeh Saraji 1, Maryam Hami 1 * , Reza Boostani 2, Mohammad Javad Mojahedi 1

1 Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2 Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
*Corresponding author: Maryam Hami, Email: hamim@mums.ac.ir

Abstract

Introduction: Restless leg syndrome (RLS) is a sensory motor disorder. Patients with this syndrome have serious and uncontrollable desire to move their legs, which is mostly due to an uncomfortable feeling intensified when they are motionless. It may be a genetic disorder or secondary to iron deficiency, neurodegenerations, pregnancy, some drugs and severe kidney diseases.

Objectives: This study was designed to find out the prevalence and its risk factors of RLS in hemodialysis patients.

Patients and Methods: This multicenter cross-sectional study was done on 260 hemodialysis patients. The prevalence of RLS was measured using International Restless Legs Syndrome Study Group (IRLSSG)’s RLS Questionnaire (RLSQ). Potential risk factors for RLS including underlying cause of chronic renal failure, duration on dialysis, biochemical tests, dialysis adequacy, and erythropoietin and also venofer dosage in recent month and demographic data were also evaluated.

Results: The prevalence of RLS was 55% including 59.4% males and 40.6% females. Their mean age of RLS patients and their dialysis duration were significantly higher than other group (P<0.05). Their body mass index (BMI) and serum calcium were significantly higher (P<0.05). However erythropoietin dosage and serum hemoglobin level were lower in RLS patients (P<0.05). Significant predictors of RLS were history of diabetes mellitus (DM), hypertension (HTN), smoking (P<0.05). There was not significant relation between RLS and dialysis adequacy, serum intact parathyroid hormone (iPTH), urea, ferritin and venofer dosage (P>0.05).

Conclusion: According to the results, RLS is a common disorder in hemodialysis patients which can affect strongly on their life. So particular attention and sooner diagnosis of RLS in high risk patients for better management is necessary.

Implication for health policy/practice/research/medical education:

In a multicenter cross-sectional study on 260 stable hemodialysis patients to detect the prevalence of RLS and its risk factors, we found its prevalence was 55% of patients. It is appeared RLS is a common disorder in hemodialysis patients and patients with past history of DM, HTN and smoking are more prone to it. So particular attention and sooner diagnosis of RLS in high risk patients for better management is necessary.

Please cite this paper as: Zadeh Saraji N, Hami M, Boostani R, Mojahedi MJ. Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. J Renal Inj Prev. 2017;6(2):137-141. DOI: 10.15171/jrip.2017.27.

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