eISSN: 2345-2781  
Submitted: 10 Aug 2017

Accepted: 15 Nov 2017
First published online: 24 Nov 2017
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J Renal Inj Prev. 2018;7(3):186-188.
doi: 10.15171/jrip.2018.44

Original

Association of interdialytic weight gain and glycosylated hemoglobin in chronic hemodialysis patients

Narges-Sadat Zahed 1, Adineh Taherkhani 2 * , Zahra Davoudi 3

1 Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding author: Adineh Taherkhani, Email: adinehtaherkhani.80@gmail.com

Abstract

Introduction: The most common cause of mortality among chronic hemodialysis (HD) patients is cardiovascular disease. Hypervolemia is an important risk factor for hypertension and cardiovascular mortality in HD patients that include chronic volume overload and interdialytic weight gain (IDWG).

Objectives: The objective of this study is to assess the role of blood glucose in IDWG.

Patients and Methods: In this cross-sectional study we enrolled 231 adult chronic HD patients. Patients with congestive heart failure, hypoalbuminemia, cirrhosis, hypothyroidism and recent blood transfusion were excluded. We weighted patients at the end of dialysis and before initiation the next dialysis in midweek dialysis sessions. Glycosylated hemoglobin (HbA1C) was measured in all patients. Patients were divided into three groups according HbA1C levels (<6%, 6-7%, >7%). Additionally IDWG of three groups was compared using analysis of variance (ANOVA) method.

Results: HbA1C was <6% in 158 (68%) patients (group A), 6-7% in 40 (17%) patients (group B) and >7% in 33 (14%) patients (group C). Mean IDWG was 2.44 kg in group A, 2.25 kg in group B and 2.71 kg in group C. In this study, no significant difference of IDWG in patients with different values of HbA1C was detected (P=0.206).

Conclusion: Our study showed that blood glucose level had no significant role in IDWG in chronic HD patients.

Implication for health policy/practice/research/medical education:

In a cross-sectional study on 231 adult chronic hemodialysis patients, we found, blood glucose level had no significant role in IDWG in chronic hemodialysis patients.

Please cite this paper as: Zahed NS, Taherkhani A, Davoudi Z. Association of interdialytic weight gain and glycosylated hemoglobin in chronic hemodialysis patients. J Renal Inj Prev. 2018;7(3):186-188. DOI: 10.15171/jrip.2018.44.

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