Submitted: 06 Feb 2018
Accepted: 14 May 2018
First published online: 10 Jun 2018
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J Renal Inj Prev. 2018;7(4):292-296.
doi: 10.15171/jrip.2018.64

Scopus id: 85054402900
  Abstract View: 195
  PDF Download: 157

Original

The effect of urinary tract infection on patient and graft survival rate in a group of kidney transplanted patients

Mousa Ghelichi Ghojogh 1, Shaker Salarilak 2 * , Ali Taghizadeh Afshari 3, Hamid Reza Khalkhali 4, Mohammad Reza Mohammadi-Fallah 3, Khadijeh Makhdoomi 5

1 School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2 Public Health Department, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 Nephrology, and Kidney Transplant Research Center, Department of Urology, Imam Medical Center, Urmia University of Medical Sciences, Urmia, Iran
4 Department of Epidemiology and Biostatistics, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran
5 Nephrology, and Kidney
*Corresponding author: Shaker Salarilak, Email: Email: salari@iaut.ac.ir

Article

Introduction: Urinary tract infection (UTI) is one of the most common infection following kidney transplant surgery.

Objectives: This study was aimed to evaluate the effect of UTI after transplant on patients and graft survival rate.

Patients and Methods: This study was cross-sectional and the data collected retrospectively. Kaplan-Meier method was used to calculate the survival rate of patients and log-rank test was applied to compare the survival curves. Cox regression model was applied for modeling the factors affecting survival rate. The data were analyzed using SPSS version 19. The level of significance considered less than 0.05.

Results: The mean duration of follow-up in infected and non-infected patients following kidney transplantation surgery were 53.78±24.5 months and 67±40.8 months, respectively. Ten-year survival rate in infected by UTI and in non-infected by UTI were 78±0.03% and 89±0.02%, respectively. Also, 10-year graft survival rate in infected patients and in noninfected patients were 71±0.03% and 88±0.02%, respectively. Log-rank test showed a significant difference between infected and non-infected patients regarding graft survival rate (P<0.001).

Conclusion: The results showed that the survival rate of patients was different in infected and non-infected patients. This finding indicated the importance of follow-up in patients with infection following kidney transplant surgery.

Implication for health policy/practice/research/medical education:

Urinary tract infection following kidney transplant is prevalent in patients who their urine culture was positive before transplant. A significant relationship between UTI and kidney survival rate was detected in our study. It should be noted that exact paraclinical evaluation of UTI is necessary before kidney transplant, during follow-up.

Please cite this paper as: Ghelichi Ghojogh M, Salarilak S, Taghizadeh Afshari A, Khalkhali HR, Mohammadi-Fallah MR, Makhdoomi K. The effect of urinary tract infection on patient and graft survival rate in a group of kidney transplanted patients. J Renal Inj Prev. 2018;7 (4):292-296. DOI: 10.15171/jrip.2018.64.

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