eISSN: 2345-2781  
J Renal Inj Prev. 2018;7(4):264-268.
doi: 10.15171/jrip.2018.59

Original

Impact of type of donor on graft and patient survival rate in kidney transplanted patients in Iran 

Mousa Ghelichi Ghojogh 1, Shaker Salarilak 2 * , Ali Taghizadeh Afshari 3, Hamid Reza Khalkhali 4, Mohammad Reza Mohammadi-Fallah 3, Khadijeh Makhdoomi 5

1 School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2 Public Health Department, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 Nephrology, and Kidney Transplant Research Center, Department of Urology, Imam Medical Center, Urmia University of Medical Sciences, Urmia, Iran
4 Department of Epidemiology and Biostatistics, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran
5 Nephrology, and Kidney Transplant Research Center, Department of Urology, Imam Medical Center, Urmia University of Medical Sciences, Urmia, Iran
*Corresponding author: Shaker Salarilak, Email: Email: salari@iaut.ac.ir

Abstract

Introduction: End-stage renal disease (ESRD( is an increasing problem in the world. Kidney transplant is considered as preferred therapeutic method for ESRD. Options for organ transplantation include living related donor (LRD), living unrelated donor (LURD) and cadaveric donor.

Objectives: This study was aimed to evaluate the effect of type of donor on graft and survival rate of patients. Patients and Methods: This study was cross-sectional, which used Meier method to calculate the patient survival rate. Additionally log-rank test was applied to compare the survival curves; analysis of variance (ANOVA) was applied to compare continuous variables and χ2 test was used to compare the data. Data were analyzed using SPSS version 19 and P values less than 0.05 was considered significant.

Results: The mean duration of follow-up in LRD, LURD and cadaveric recipients were 60.37±34.2, 79.17±33 and 61.17±34 months respectively. Five-year survival, in LRD was 100 months, in LURD recipients was 87±0.01 months, and in cadaveric recipients was 91±0.03 months. The mean survival of graft in LRD, LURD and cadaveric recipients were 115.5±3.1, 103.27±1.2 and 102.15±4.5 months, respectively. Log-rank test showed a significant difference between graft survival in recipients (P=0.038).

Conclusion: The results showed that LRD is one of the factors affecting graft survival. Hence, graft survival rate showed high length among patients who their graft was from LRD compared to LURD and cadaveric.

Implication for health policy/practice/research/medical education:

Given that the survival rate of the transplanted kidney in patients from relatives is more than others (not relatives), it is recommended that in priority choose alive relatives as a kidney donor in transplant centers.

Please cite this paper as: Ghelichi Ghojogh M, Salarilak S, Taghizadeh Afshari A, Khalkhali HR, Mohammadi-Fallah MR, Makhdoomi K. Impact of type of donor on graft and patient survival rate in kidney transplanted patients in Iran. J Renal Inj Prev. 2018;7(4):264-268. DOI: 10.15171/jrip.2018.59.

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