eISSN: 2345-2781  
Submitted: 20 Aug 2017

Accepted: 13 Dec 2017
First published online: 06 Jan 2018
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J Renal Inj Prev. 2019;8(1):62-64.
doi: 10.15171/jrip.2019.12

Case Report

A case of crescentic glomerulonephritis associated with relapsing polychondritis

Bahman Bashardoust 1 * , Ahmad Sabzevari 1, Mojgan Asgari 2

1 Department of Nephrology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
2 Department of Pathology, Hospital Management and Research Center (HMRC), Iran University of Medical Science, Tehran, Iran
*Corresponding author: Bahman Bashardoust, Email: Email: b_bashardoust@yahoo.com

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease, characterized by recurrent inflammatory episodes affecting various carttilageus structures. Renal involvement in RP is unusual. Our case was a 42-year old woman presented with nephretic syndrome. Diagnosis of RP was made because of recurrent chondritis of both auricles, chondritis of costovertebral joints, non-erosive inflammatory arthritis of knees, and inflammation of ocular structures. Renal biopsy findings revealed diffuse crescentic and sclerotic glomerulonephritis, pauciimmune type. The diagnosis of RP may be missed when the destructive cartilage feature is not apparent or rare presentation of disease such as ocular or renal involvement preceded other manifestations. In this case we found that the irregular prednisolone use may prevent destructive cartilage damage but not renal failure of patient. We concluded that the association of crescentic glomerulonephritis in a patient with RP was assumed to be a rare manifestation of this disease.

Implication for health policy/practice/research/medical education:

The association of crescentic glomerulonephritis in a patient with relapsing polychondritis was assumed to be a rare manifestation of this disease.

Please cite this paper as: Bashardoust B, Sabzevari A, Asgari M. A case of crescentic glomerulonephritis associated with relapsing polychondritis. J Renal Inj Prev. 2019;8(1):62-64. DOI: 10.15171/jrip.2019.12.

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