First published online: 01 Sep 2012
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J Renal Inj Prev. 2012;1(2).
doi: 10.12861/jrip.2012.20
PMID: 25340109
PMCID: PMC4205986
  Abstract View: 875
  PDF Download: 588

Original Article

Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients

Hamid Nasri *

1 Department of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran
Corresponding author: Hamid Nasri M.D, Department of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran. Email: hamidnasri@yahoo.com

Article

Introduction: Numerous studies have attempted to identify risk factors for mortality and morbidity in maintenance hemodialysis patients. In this study we sought to examine the association of the levels of serum C-reactive protein (CRP) with value of Ca×PO4 product, in stable hemodialysis patients. Patients and Methods: Based on the severity of secondary hyperparathyroidism, patients being treated with oral active vitamin D3, calcium carbonate/Renagel tablets at various doses. Fasting serum 25-hydroxy vitamin D and intact serum parathormone and also serum blood urea nitrogen, CRP, calcium, phosphorus, alkaline phosphatase was measured. Results: A total of 41 patients, enrolled to the study. The mean patients’ age were 46(17.6) years. The value of serum CRP of patients was 8.6 (6.6) mg/l (median 6 mg/l). The value of Ca×PO4 product was 50.5(15.5) mg2/dl2 (median: 50 mg2/dl2). In this study, a significant inverse association between Ca×PO4 product and the age of the patients was seen. A significant positive correlation of logarithm of serum CRP with Ca×PO4 product was found. Conclusion: The result of this study, revealed the need to further attention to hyperphosphatemia in hemodialysis patients.
Implication for health policy/practice/research/medical education: In a study on 41stable hemodialysis patients, we found a significant positive correlation of serum C-reactive protein with Ca×PO4 product. The result of this study, revealed the need to further attention to hyperphosphatemia in hemodialysis patients. Please cite this paper as: Nasri H. Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients. J Ren Inj Prev 2012; 1(2):55-59. DOI: 10.12861/jrip.2012.20
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