First published online: 01 Dec 2012
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J Renal Inj Prev. 2012;1(1).
doi: 10.12861/jrip.2012.02
PMID: 25340091
PMCID: PMC4205984
  Abstract View: 830
  PDF Download: 589

Mini-Review

Silymarin and diabetic nephropathy

Mahmoud Rafieian-Kopaie 1 * , Hamid Nasri 2

1 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding author: Prof. Mahmoud Rafieian-Kopaei, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. Email: rafieian@yahoo.com

Article

Nephropathy is one of the most important complications of diabetes mellitus and drug induced toxicity. Nephrotoxicity is mostly related to oxidative stress and nowadays much attention has been made towards the possible kidney protective properties of medicinal plants. Studies revealed, silymarin is useful for diabetic nephropathy. The combination of metformin, silymarin and renin-angiotensin system inhibitors or angiotensin receptor blockers may have additive kidney protective property to prevent or slowing the progression of diabetic nephropathy.
Please cite this paper as: Rafieian-Kopaie M, Nasri H. Silymarin and diabetic nephropathy. J Ren Inj Prev 2012; 1(1): 3-5.
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