First published online: 01 Mar 2013
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)

J Renal Inj Prev. 2013;2(1).
doi: 10.12861/jrip.2013.06
PMID: 25340115
PMCID: PMC4205996
  Abstract View: 991
  PDF Download: 527

Short Communication

IgG deposition in IgA nephropathy patients

Hamid Nasri 1 *

1 Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding author: Prof. Hamid Nasri, Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran. Email: hamidnasri@yahoo.com

Article

IgA nephropathy is the most common form of glomerular disease among young adults. The aim of this study is to determine the correlation of IgG deposition with morphologic variables of Oxford classification and some clinical data of patients with IgA nephropathy (IgAN).A total of 114 biopsies were enrolled to the study (70.2% were male). Mean age of the patients was 37.7±13.6 years. This study showed that, IgG deposition intensity had not significant correlation with serum creatinine. No significant association of sex with IgG was found. There was not significant association of IgG deposits with age below and more that 40 years. There was not significant association of IgG deposit intensity with four morphologic variables of Oxford classification. Less studied published regarding the immunostaining findings in IgA nephropathy patients. Location of deposited immunoglobulin (mesangial versus mesangial-capillary) or the type of immunoglobulin (IgG or IgM) may have prognostic significant. More studies needs to find the clinical significance of immunostaining data.
Implication for health policy/practice/research/medical education:
Less studied published regarding the immunostaining findings in IgA nephropathy patients. Location of deposited immunoglobulin (mesangial versus mesangial-capillary) or the type of immunoglobulin (IgG or IgM) may have prognostic significant. More studies needs to find the clinical significance of immunostaining data.

Please cite this paper as: Nasri H. IgG deposition in IgA nephropathy patients. J Ren Inj Prev 2013; 2(1): 11-13.
First name
 
Last name
 
Email address
 
Comments
 
Security code


Article Viewed: 991

Your browser does not support the canvas element.


PDF Downloaded: 527

Your browser does not support the canvas element.