First published online: 14 Nov 2013
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J Renal Inj Prev. 2014;3(1).
doi: 10.12861/jrip.2014.11
PMID: 25340162
PMCID: PMC4206039
  Abstract View: 856
  PDF Download: 538

Commentary

Comment on ; Post-infectious glomerulonephritis presenting as acute renal failure in a patient with Lyme disease

Hamid Nasri 1 *

1 Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding author: Prof. Hamid Nasri, Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran. Email: hamidnasri@yahoo.com

Article

Implication for health policy/practice/research/medical educationMost cases of IgA nephropathy (IgAN) are idiopathic, however, various diseases are associated with IgAN. Recent findings have suggested that IgAN may be a consequence of infections, possibly due to an abnormal IgA-mediated immune response against microbial antigens with formation of nephrotoxic immune complexes. It is possible that removal of the causative organism from circulation by appropriate treatment leads to improvements in kidney function through increased clearance of immune-complexes, thus leading to the resolution of IgA nephropathy.
Please cite this paper as: Nasri H. Comment on; Post-infectious glomerulonephritis presenting as acute renal failure in a patient with Lyme disease. J Ren Inj Prev 2014; 3(1):35-36. DOI: 10.12861/jrip.2014.11
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