John W Pickering
1*, Zoltán H Endre
21 Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand
2 Department of Nephrology, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
*Corresponding Author: *Corresponding author: Assoc. Prof. John W Pickering, Department of Medicine, University of Otago Christchurch, Private Bag 4345, Christchurch 8140, New Zealand., Email:
john.pickering@icloud.com
Abstract
The first consensus definition of Acute Kidney Injury (AKI) was published a decade ago. In this mini narrative review we look at the history of the changes in the definition of AKI and consider how it may change again in the near future. The epidemiology of small changes in creatinine and the difficulties with determining baseline creatinine have driven the changes. Recent evidence on urinary output and the application of structural injury biomarkers are likely to change the definition once more.
Implication for health policy/practice/research/medical education:
The first consensus definition of Acute Kidney Injury (AKI) was published a decade ago. In this mini narrative review we look at the history of the changes in the definition of AKI and consider how it may change again in the near future. The epidemiology of small changes in creatinine and the difficulties with determining baseline creatinine have driven the changes. Recent evidence on urinary output and the application of structural injury biomarkers are likely to change the definition once more.
Please cite this paper as: Pickering JW, Endre ZH. The definition and detection of acute kidney injury. J Ren Inj Prev 2014; 3(1):21-25.
Doi: 10.12861/jrip.2014.08