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ePublished: 10 Apr 2014
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J Renal Inj Prev. 2014;3(2): 55-56.
doi: 10.12861/jrip.2014.18
PMID: 25340169
PMCID: PMC4206050
  Abstract View: 1146
  PDF Download: 666

Commentary

Antioxidants against contrast media induced nephrotoxicity

Majid Tavafi *

1 Department of anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran
*Corresponding author: Majid Tavafi, Department of anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran. mtavafi@yahoo.com

Abstract

Implication for health policy/practice/research/medical educationAlthough intravascular injection of contrast media is very important in diagnostic radiology but may lead to acute renal failure and hospitalization. It seems that, pathogenesis of contrast media nephrotoxicity acts through renal vasoconstriction, medullary ischemia, tubular cell death and production of reactive oxygen species. Pretreatment with antioxidants attenuated renal side effects of contrast media in patients and laboratory animals.
Keywords: Contrast media, Nephrotoxicity, Antioxidant
Please cite this paper as: Tavafi M. Antioxidants against contrast media induced nephrotoxicity. J Renal Inj Prev 2014; 3(2):55-56. DOI: 10.12861/jrip.2014.18
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