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Submitted: 04 Apr 2020
Accepted: 09 Jul 2020
ePublished: 13 Aug 2020
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J Renal Inj Prev. 2021;10(3): e18.
doi: 10.34172/jrip.2021.18
  Abstract View: 65
  PDF Download: 24

Review

A systematic review of the relationship between acute tubular necrosis and kidney transplantation

Arezo Elmi 1 ORCID logo, Mohammad Arabsorkhi Mishabi 2 ORCID logo, Esmaeil Teymoori 2 ORCID logo, Dorrin Nikbakht 2 ORCID logo, Nazanin Sarraf 2, Fatemeh Jabinian 3, Abbas Khalilpour 2 ORCID logo, Afsaneh Askarkhah 4, Vahid Rahmani 5,2 * ORCID logo

1 Shohada Educational Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Operating Room, Iran University of Medical Sciences, Tehran, Iran
3 Department of Operating Room, Shahid Sadoughi University of Medical Sciences, Yazd, iran
4 Department of Operating Room, Guilan University of Medical Sciences, Rasht, Iran
5 Department of Operating Room, Maragheh University of Medical Sciences, Maragheh, Iran
*Corresponding author: Vahid Rahmani, Email: v.rahmani@mrgums.ac.ir

Abstract

Introduction: Acute tubular necrosis (ATN) is a common syndrome following kidney transplantation. In this study, we reviewed systematically the relationship between ATN and kidney transplantation.

Materials and Methods: International databases including PubMed, Web of Science and Scopus were considered for search of English articles by Aug 2019. Seven published articles were finally entered into the study. Keywords were ATN, acute kidney injury, kidney transplantation and renal transplantation or a combination of them in the title/abstracts.

Results: There were seven published articles (conducted on 2,534 individuals) reviewed in this systematic review consisted of two retrospective, three prospective studies and two clinical trial studies.

Conclusion: The administration of cyclosporine immediately following kidney transplantation is a predicting factor for development of ATN. According to the results, ATN can be associated with kidney transplantation, especially transplanted from deceased donors.


Keywords: Acute tubular necrosis, Acute kidney injury, Kidney transplantation, Cyclosporine

Implication for health policy/practice/research/medical education:

Administration of cyclosporine immediately following kidney transplantation is a predicting factor for development of acute tubular necrosis.

Please cite this paper as: Elmi A, Arabsorkhi Mishabi M, Teymoori E, Nikbakht D, Sarraf N, Jabinian E, et al. A Systematic review of the relationship between acute tubular necrosis and kidney transplantation. J Renal Inj Prev. 2021; 10(3): e18. doi: 10.34172/jrip.2021.18.


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