Submitted: 10 Sep 2020
Accepted: 10 Nov 2020
ePublished: 24 Nov 2020
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J Renal Inj Prev. 2021;10(2): e16.
doi: 10.34172/jrip.2021.16
  Abstract View: 51
  PDF Download: 19

Case Report

Unusual presentation of acute kidney injury with Tumour Lysis Syndrome

Mirza Yasar Baig 1 * ORCID logo, Rajkumar Chinnadurai 1 ORCID logo, Constantina Chrysochou 1 ORCID logo

1 Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, UK
*Corresponding author: Mirza Yasar Baig, Email: mirza.baig@srft.nhs.uk


Tumour lysis syndrome (TLS) can cause acute kidney injury (AKI) by the breakdown of intracellular contents during treatment for malignancies with large tumour burden. We report a case with an unusual presentation of AKI needing renal replacement therapy. Investigation of the cause for AKI led to the diagnosis of an underlying malignancy (lymphoma). Treatment of a Bell’s palsy with steroids before presenting to our service has caused the AKI giving us the overarching diagnosis of TLS in this patient with lymphoma.
Keywords: Tumour lysis syndrome, Acute kidney injury, Rasburicase
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