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Submitted: 22 Jul 2021
Accepted: 01 Sep 2021
ePublished: 18 Sep 2021
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J Renal Inj Prev. 2022;11(1): e1-e1.
doi: 10.34172/jrip.2022.01
  Abstract View: 527
  PDF Download: 279

Original

Prevalence and predisposing factors of chronic kidney disease in Yazd city; a population-based study

Masoud Mirzaei 1 ORCID logo, Nader Nourimajalan 2 * ORCID logo, Hamidreza Morovati 3 ORCID logo, Mohsen Askarishahi 4 ORCID logo, Roya Hemayati 5 ORCID logo

1 Yazd Cardiovascular Research Centre, Shahid Sadoughi University, Yazd, Iran
2 Division of Nephrology, Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3 Department of Statistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4 Department of Biostatistics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5 Division of Nephrology, Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
*Corresponding author: Nader Nourimajalan, Email: dr_nori_majelan@yahoo.com

Abstract

Introduction: Chronic kidney disease (CKD) is a major health problem and one of the public health threats with an increasing prevalence and burden. However, early diagnosis of this disease is challenging in Iran due to insufficient information.

Objectives: In the present study, we aimed to determine the prevalence of CKD and its predisposing factors in Yazd city, Iran.

Patients and Methods: We conducted this cross-sectional study using the recruitment phase data of Yazd Health Study (YaHS) collected during 2013-2014. Data of 3649 individuals, age 20-69 years were analyzed. Glomerular filtration rate (GFR) was calculated using the modification of diet in renal disease (MDRD) formula and values less than 60 mL/min/1.73 m2 were defined as CKD. Logistic regression was employed to determine the risk factors of CKD.

Results: The mean age of participants was 46.0 ± 13.8 years and the overall prevalence of CKD was 6.6 percent (7.6% for women and 5.4% for men). The disease prevalence was 21.5% in the age group of 60-69 years. The prevalence of CKD had a significant relationship with older age, obesity, female gender, diabetes, high blood pressure and history of heart disease.

Conclusion: CKD has a high prevalence in the population of this region of Iran. The most important modifiable risk factors for CKD included diabetes and high blood pressure. Therefore, the health system should strive for early detection of CKD in order to prevent morbidity and mortality of this disease.


Keywords: Chronic kidney disease, Glomerular filtration rate, Prevalence, Risk factor

Implication for health policy/practice/research/medical education:

In a population-based study on 3649 participants in central of Iran, Yazd city, the overall prevalence of chronic kidney disease (CKD) was 6.6%. The most important modifiable risk factors for CKD included diabetes and high blood pressure. The health system should strive for early detection of CKD in order to prevent morbidity and mortality of CKD, especially in this region of Iran.

Please cite this paper as: Mirzaei M, Nourimajalan N, Morovati H, Askarishahi M, Hemayati R. Prevalence and predisposing factors of chronic kidney disease in Yazd city; a population-based study. J Renal Inj Prev. 2022; 11(1): e01. doi: 10.34172/jrip.2022.01.


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