Submitted: 14 Nov 2018
Accepted: 10 Jan 2019
First published online: 28 Jan 2019
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J Renal Inj Prev. 2019;8(2):140-145.
doi: 10.15171/jrip.2019.26
  Abstract View: 146
  PDF Download: 143

Original

Prognosis of acute kidney injury based on pRIFLE criteria among patients admitted to pediatric intensive care unit in Northern Iran; a single center study

Afshin Safaei-Asl 1 * , Mahsa Jilani 1, Abtin Heydarzadeh 2, Shohreh Maleknejad 1

1 Department of Pediatrics, Guilan University of Medical Sciences, Guilan, Iran
2 Department of Community Medicine, Guilan University of Medical Sciences, Guilan, Iran
*Corresponding author: Afshin Safaei-Asl, Email: Email: afshin_safaei2@yahoo.com

Article

Introduction: Acute kidney injury (AKI) is a frequent problem in pediatric intensive care units, while it is associated with significant mortality.

Objectives: The aim of this study was to determine the prevalence and prognosis of AKI based on pRIFLE (pediatric risk, injury, failure, loss, end-stage renal disease) criteria among children admitted to a pediatric intensive care unit

Patients and Methods: This research included 323 children from 1 month to 14 years old age, admitted to the pediatric intensive care unit. The pRIFLE was determined in patients along with urinary output and creatinine level. The pediatric risk of mortality (PRISM) score was also assessed.

Results: Mean PRISM III score was 34.66 ± 15.97 and 17.72 ± 6.06 respectively in children with and without AKI (P=0.001). It was found that variables of encephalopathy, PRISMIII score and gender were the only variables affecting the incidence of AKI.

Conclusion: While pRIFLE criteria are appropriate and efficient criteria for early diagnosis of AKI, their role alone as prognostic factors of mortality require further studies.

Implication for health policy/practice/research/medical education:

The pRIFLE (pediatric risk, injury, failure, loss, end-stage renal disease) criteria adapted from the RIFLE criteria for use in children. This study was to determine the prevalence and prognosis of AKI based on pRIFLE criteria among children admitted to a pediatric intensive care unit. Although pRIFLE is appropriate and efficient criteria for early diagnosis of AKI to speed up treatment and reduce the incidence of AKI complications, its role alone as a prognostic factor of mortality requires further studies.

Please cite this paper as: Safaei-Asl A, Jilani M, Heydarzadeh A, Maleknejad S. Prognosis of acute kidney injury based on pRIFLE criteria among patients admitted to pediatric intensive care unit in Northern Iran; a single center study. J Renal Inj Prev. 2019;8(2):140-145. DOI: 10.15171/jrip.2019.26

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