Sepideh Zununi-Vahed
1, Mohammadreza Ardalan
1*, Fariba Mahmoodpoor
1, Kasra Ardalan
2, Ramin Tolouian
31 Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Faculty of Pharmacy, Eastern Mediterranean University, Famagusta, Turkish Republic of North Cyprus
3 Division of Nephrology and Hypertension, University of Central Florida, college of medicine, Orlando, FL, USA
Abstract
Herbal medicine has grabbed the public interest and there is a general belief of their safety and life compatibility. There are growing proportion of reported side effects of herbal medicine in past years. We reported a 62-year-old woman who developed acute interstitial nephritis (AIN) accompanied by autoimmune hemolytic anemia (AIHA), three weeks after daily ingestion of heat extract of fenugreek. The patient’s renal, hematologic and liver panels were improved after steroid pulse therapy and fenugreek discontinuation. Fenugreek contains high amount of flavonoid which might be a main culprit for AIN and AIHA.
Implication for health policy/practice/research/medical education:
Fenugreek (Trigonella foenum-graecum) contains high amount of flavonoid which might be a main culprit for AIN and AIHA.
Please cite this paper as: Zununi-Vahed S, Ardalan MR, Mahmoodpoor FM, Ardalan K و Tolouian R. Fenugreek (Trigonella foenum-graecum) induced interstitial nephritis. J Renal Inj Prev. 2017;6(4):286-288. DOI: 10.15171/jrip.2017.54.