Nasiba Satibaldiyeva
1* 
, Azadaxon Yuldasheva
2 , Nargiza Yusupova
3 , Nigina Saidova
4 , Fazila Zokirova
5 , Maftuna Usmonova
6 , Zuxriddin Zokirov
7 , Dildora Babaxanova
8 , Dilnoza Achilova
9 , Matluba Suyarova
10 1 Department of Children’s Disease, Tashkent State Medical University, Tashkent, Uzbekistan
2 Department of Obstetrics and Gynecology, Andijan State Medical Institute, Andijan, Uzbekistan
3 Department of Clinical Laboratory Diagnostics, Samarkand State Medical University, Samarkand, Uzbekistan
4 Department of Medical Radiology and Nuclear Medicine, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
5 Department of Rehabilitation, Sports Medicine and Physical Education, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
6 Department of Medical and Biological Chemistry, Fergana Medical Institute of Public Health, Fergana, Uzbekistan
7 Pediatrician and Nephrologist, Bukhara Regional Multidisciplinary Children’s Medical Center, Bukhara, Uzbekistan
8 Department of Economics in the ICT Sector, Tashkent University of Information Technologies named after Muhammad al Khwarizmi, Tashkent, Uzbekistan
9 Department of Applied French Language Studies, Uzbekistan State World Languages University, Uzbekistan
10 Jizzakh Polytechnic Institute, Jizzakh, Uzbekistan
Abstract
Chronic kidney disease (CKD) affects millions globally and is associated with high morbidity and mortality, including cardiovascular complications and progression to end-stage kidney disease (ESKD). Primary care practitioners play a critical role in early identification, risk stratification, and management of CKD due to the often asymptomatic nature of early-stage disease and the high prevalence of comorbidities such as diabetes and hypertension. World kidney day (WKD) serves as a vital platform to raise kidney health awareness, highlight the importance of early detection, and display advances in CKD management. Recent innovations in primary care, including refined risk stratification and emerging therapies such as SGLT2 inhibitors, GLP1 receptor agonists, and new drug classes, are transforming CKD treatment paradigms.
Implication for health policy/practice/research/medical education:
World kidney day (WKD) serves as a vital platform to raise kidney health awareness, highlight the importance of early detection, and showcase advances in chronic kidney disease (CKD) management. CKD is a growing global health burden, affecting approximately 10% of the world’s population. As a progressive condition often asymptomatic in its early stages, CKD poses significant challenges for early diagnosis and timely intervention. Primary care providers are at the forefront of CKD management, playing a critical role in early detection, risk stratification, and the implementation of evidence-based interventions to slow disease progression and reduce cardiovascular morbidity and mortality. Recent advances in screening tools, biomarkers, risk prediction models, and therapeutic strategies have significantly enhanced the ability of primary care to manage CKD effectively. Fortunately, recent innovations in primary care, including refined risk stratification and emerging therapies such as SGLT2 inhibitors, GLP1 receptor agonists, and new drug classes, are transforming CKD treatment paradigms.
Please cite this paper as: Satibaldiyeva N, Yuldasheva A, Yusupova N, Saidova N, Zokirova F, Usmonova M, Zokirov Z, Babaxanova D, Achilova D, Suyarova M. Advances in primary care approaches to chronic kidney disease; early identification, risk stratification, and cutting-edge therapies–a world kidney day overview. J Renal Inj Prev. 2026; 15(4): e38762. doi: 10.34172/jrip.38762.