Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 2 3 2013 09 10 Significance of hyperuricemia in immunoglobulin A nephropathy 105 106 10.12861/jrip.2013.33 EN Hamid Nasri Mohammad Reza Ardalan Journal Article 10.12861/jrip.2013.33 Implication for health policy/practice/research/medical education:It is well known that hyperuricemia is an independent risk factor for renal progression in IgA nephropathy, however it is unclear the effect of allopurinol therapy, on the clinical outcome in hyperuricemic IgAN. It is possible that appropriate treatment by allopurinol be a reasonable modality in these patients. However, to better understand the kidney protective efficacy of allopurinol in IgAN patients, more clinical studies are suggested.