Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 2 4 2013 12 01 Significance of segmental glomerulosclerosis in IgA nephropathy: What is the evidence? 113 115 10.12861/jrip.2013.36 EN Muhammed Mubarak Hamid Nasri EDITORIAL 10.12861/jrip.2013.36 Implication for health policy/practice/research/medical educationPrimary IgA nephropathy (IgAN) is the commonest glomerulopathy worldwide. Its clinical presentation, histology and prognosis vary widely. The lesions of segmental glomerulosclerosis are common in IgAN and represent participation of at least three pathogenetic mechanisms. It is important to identify the different subtypes of segmental sclerosing lesions as these are of prognostic value.