Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 10 3 2021 09 01 Epidemiological, clinical and morphological aspects of kidney damage in COVID-19 e17 e17 10.34172/jrip.2021.17 EN Batir Daminov https://orcid.org/0000-0001-9594-1732 Sherzod Abdullaev https://orcid.org/0000-0003-0640-5976 Olimkhon Sharapov https://orcid.org/0000-0003-2452-416X Ranokhon Igamberdieva https://orcid.org/0000-0002-7314-0309 Journal Article 10.34172/jrip.2021.17 2021 02 14 2021 03 09 The mini-review presents modern data on the epidemiology, clinical and morphological aspects of kidney damage in COVID-19. Potential mechanisms of kidney involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are especially important for individuals undergoing extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue with damage to tubular epithelial cells and podocytes, and erythrocyte aggregation in persons with severe COVID-19. By including people with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated.