Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 13 2 2024 04 21 Management of a newly diagnosed case of myeloma kidney in a recently COVID-19 recovered patient e31948 e31948 10.34172/jrip.2022.31948 EN Muthukaruppaiah Suganya https://orcid.org/0000-0002-7414-3210 Varadharajan Jayaprakash https://orcid.org/0000-0002-6886-9015 Vasudevan Manimoliyan Duraimavalavan Mathew Gerry George https://orcid.org/0000-0003-1967-4470 Raghavan Padmanabhan Sailapathy Sreedhar https://orcid.org/0000-0001-9574-7403 Journal Article 10.34172/jrip.2022.31948 2021 08 11 2021 10 04 Multiple myeloma is a malignant monoclonal plasma cell disorder occurring predominantly in the elderly population. Outcomes of coronavirus disease 2019 (COVID-19) are worse in elderly, persons with comorbid conditions such as malignancy and patients who are on immunosuppressive therapy. Here we report a case, in which COVID-19 unravelled the diagnosis of multiple myeloma and myeloma cast nephropathy. Bortezomib-based two drug induction immunosuppression, was given during the peak of second wave of COVID-19, and it resulted in clinical improvement and partial remission of multiple myeloma.