﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Nickan Research Institute</PublisherName>
      <JournalTitle>Journal of Renal Injury Prevention</JournalTitle>
      <Issn>2345-2781</Issn>
      <Volume>12</Volume>
      <Issue>4</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2023</Year>
        <Month>12</Month>
        <DAY>01</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>Factors related to mortality in hemodialysis patients with COVID-19</ArticleTitle>
    <FirstPage>e32005</FirstPage>
    <LastPage>e32005</LastPage>
    <ELocationID EIdType="doi">10.34172/jrip.2022.32005</ELocationID>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Gulay</FirstName>
        <LastName>Yilmaz</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0001-6565-8063</Identifier>
      </Author>
      <Author>
        <FirstName>Ozge</FirstName>
        <LastName>Timur</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-7296-5536</Identifier>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">10.34172/jrip.2022.32005</ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>12</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2022</Year>
        <Month>01</Month>
        <Day>30</Day>
      </PubDate>
    </History>
    <Abstract>Introduction: The mortality rate in COVID-19 patients is about 2%, however advanced age, male gender, comorbid diseases increase the risk of mortality. Patients with end-stage renal disease (ESRD) and hemodialysis (HD) treatment are more susceptible to infection due to both existing comorbid diseases and immune suppression caused by uremia. Objectives: This study aims to show the potential of easily obtainable, inexpensive and reproducible markers in predicting mortality in HD patients at the time of diagnosis. Patients and Methods: In this study, we examined the relationship between; neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV) and C-reactive protein (CRP)/albumin values at the time of hospital admission with mortality in 75 HD patients diagnosed with COVID-19. All analyses were conducted using IBM SPSS Statistics 21.0 and MS-Excel 2010 software. Results: A total of 75 HD patients diagnosed with COVID-19 were included in the study. Out of these, at least 19 (25.3%) patients received hydroxychloroquine, 68 (90.6%) patients favipiravir, two (2.6%) patients tocilizumab and two patients (2.6%) immune plasma therapy. Among these patients, sixteen patients (21.3%) needed invasive mechanic ventilation, eight patients (10.6%) needed high flow oxygen and seven patients (9.3%) needed non-invasive mechanic ventilation and 17 of 75 patients (23%) died. A total of 14 of the 17 non-survivors were intubated. In comparison between survivors and non-survivors in our study; NLR, MPV, CRP, CRP/albumin and phosphorus values were significantly higher in the non-survivors group. Conclusion: According to this study, NLR, MPV and CRP/albumin values are associated with mortality in HD patients affected with COVID-19.</Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">COVID-19</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Hemodialysis</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Mortality</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Neutrophil-lymphocyte ratio</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">C-reactive protein</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>