Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 13 2 2024 04 21 Prevalence and predicting factors of acute kidney injury due to methanol intoxication; a systematic review e32195 e32195 10.34172/jrip.2023.32195 EN Mohammad Hesam Gharaeikhezri https://orcid.org/0000-0002-0129-0578 Farinaz Fattahi https://orcid.org/0000-0003-4223-1600 Pegah Karami https://orcid.org/0000-0002-7031-5628 Arash Izadpanah Ghahremani https://orcid.org/0009-0003-9038-3710 Bareza Rezaei https://orcid.org/0000-0002-7210-4162 Hooman Rafiei https://orcid.org/0000-0002-8598-9836 Hamidreza Khodabandeh https://orcid.org/0009-0005-9354-1037 Aisan Ghasemi Oskui https://orcid.org/0000-0002-0201-7629 Farshad Gharebakhshi https://orcid.org/0000-0001-5495-609X Mohammad Reza Rezaei https://orcid.org/0000-0002-5166-9711 Journal Article 10.34172/jrip.2023.32195 2023 04 05 2023 06 08 Introduction: Methanol intoxication and subsequence acute kidney injury (AKI) can be dangerous and deadly in case of a missed or delayed diagnosis; therefore, identifying its prevalence and predictor factors is necessary. Objectives: This study was conducted to identify the prevalence and predictor factors of AKI in methyl alcohol-intoxicated patients. Methods and Materials: The search strategy was conducted with the standard keyword in the international database, including Web of Science, Scopus, PubMed /Medline, Embase, Cochrane, WorldCat, Dimension, OpenGrey, EBSCO, DOAJ, CINAHL, and Google scholar search engines. Studies that reported the prevalence of AKI due to methanol poisoning were included in this review study. Results: Results demonstrated that six studies from five countries, with a sample size of 816 methanol intoxication patients, were included in this study. Mean AKI prevalence in all reviewed studies was 28.18%; Gender male, hypertension, older age, anemia, alcohol addiction, metabolic acidosis, high blood osmolality, high Formate concentration, alcohol overdose, sepsis, rhabdomyolysis, acute pancreatitis, and volume depletion were the reported AKI predictors in the reviewed studies. Conclusion: Identifying the AKI prevalence and its predictor factors in patients with methanol intoxication can help in their quick diagnosis, timely treatment, and reduce the subsequent complications.