Nickan Research Institute Journal of Renal Injury Prevention 2345-2781 7 4 2018 12 01 Potential adverse effects of amphetamines on kidney; a narrative review on current knowledge 218 223 10.15171/jrip.2018.51 EN Tahmineh Mokhtari Ardeshir Sheikhazadi Gholamreza Hassanzadeh Manouchehr Safari Fatemeh Sheikhbahaei Hedyeh Faghir-Ghanesefat Maryam Rezaei Journal Article 10.15171/jrip.2018.51 2017 10 09 2017 12 08 This study aims to review the literature pertaining to the renal effects of amphetamines (AMPs) including AMP and its analogues (ARDAs) such as methamphetamine (MET) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) and discuss the implications for these drugs users. The study was performed through searching in the relevant literature. Sufficient clinical and experimental evidence suggested that AMPs have adverse and potentially nonfatal and fatal effects on users’ kidneys. The acute and chronic renal complications due to illicit drugs such as AMPs have been investigated. A few renal effects in AMPs users have been demonstrated. However, isolated reports of adverse renal effects of AMPs including nephropathy due to rhabdomyolysis, necrotizing renal vasculopathy and malignant hypertension have been recorded. It can be suggested that renal damages after AMPs consumption should be considered in the emergency departments (EDs).