An ethnobotanical study of medicinal plants administered for the treatment of hypertension

Babak Baharvand-Ahmadi ¹, Mahmoud Bahmani ², Pegah Tajeddini ³, Mahmoud Rafieian-Kopaei ³, Nasrollah Naghdi ² *

Cited by CrossRef: 40

1- Puteri M, Afifah N, Mathriul A, Wicaksono F, Sugiarti M, Izzatinisa R, Kato M, Saputri F, Natalini B. Antiplatelet Effects of a Combination of Sappan Wood (Caesalpinia sappan L.) and Red Ginger (Zingiber officinale var. Rubrum) Extracts in a High‐Fat Diet‐Induced Rat Model. Advances in Pharmacological and Pharmaceutical Sciences. 2024;2024(1) [Crossref]

2- Kamyab R, Namdar H, Torbati M, Ghojazadeh M, Araj-Khodaei M, Fazljou S. Medicinal Plants in the Treatment of Hypertension: A Review. Adv Pharm Bull. 2020;11(4):601 [Crossref]

3- Lombardi V, Carrera I, Cacabelos R, Sulsen V. In Vitro Screening for Cytotoxic Activity of Herbal Extracts. Evidence-Based Complementary and Alternative Medicine. 2017;2017(1) [Crossref]

4- Mara de Menezes Epifanio N, Rykiel Iglesias Cavalcanti L, Falcão dos Santos K, Soares Coutinho Duarte P, Kachlicki P, Ożarowski M, Jorge Riger C, Siqueira de Almeida Chaves D. Chemical characterization and in vivo antioxidant activity of parsley (Petroselinum crispum) aqueous extract. Food Funct. 2020;11(6):5346 [Crossref]

5- Akaberi M, Boghrati Z, Amiri M, Khayyat M, Emami S. A Review of Conifers in Iran: Chemistry, Biology and their Importance in Traditional and Modern Medicine. CPD. 2020;26(14):1584 [Crossref]

6- Dogara A, Hamad S, Hama H, Bradosty S, Kayfi S, Al-Rawi S, Lema A, Khong H. Biological Evaluation of Garcinia kola Heckel. Advances in Pharmacological and Pharmaceutical Sciences. 2022;2022:1 [Crossref]

7- Ajeigbe O, Oboh G, Ademosun A, Oyagbemi A. Fig leaves varieties reduce blood pressure in hypertensive rats through modulation of antioxidant status and activities of arginase and angiotensin-1 converting enzyme. Comp Clin Pathol. 2021;30(3):503 [Crossref]

8- Kopp T, Abdel-Tawab M, Mizaikoff B. Extracting and Analyzing Pyrrolizidine Alkaloids in Medicinal Plants: A Review. Toxins. 2020;12(5):320 [Crossref]

9- Menetrier J, Bonkoski V, Medeiros K, Estevan D, Palozi R, Lívero F, Velasquez L, Lourenço E, Gasparotto Junior A. Ethnomedicinal Plants Used for the Treatment of Cardiovascular Diseases by Healers in the Southwestern State of Paraná, Brazil, and Their Validation Based on Scientific Pharmacological Data. J Relig Health. 2020;59(6):3004 [Crossref]

10- Ajeigbe O, Ademosun A, Oboh G. Relieving the tension in hypertension: Food–drug interactions and anti‐hypertensive mechanisms of food bioactive compounds. J Food Biochem. 2021;45(3) [Crossref]

11- Amtaghri S, Slaoui M, Eddouks M. Moroccan Antihypertensive Plants and their Mechanisms of Action. EMIDDT. 2024;24(11):1254 [Crossref]

12- Guzman E, Molina J. The predictive utility of the plant phylogeny in identifying sources of cardiovascular drugs. Pharmaceutical Biology. 2018;56(1):154 [Crossref]

13- Duda Ł, Kłosiński K, Budryn G, Jaśkiewicz A, Kołat D, Kałuzińska-Kołat Ż, Pasieka Z. Medicinal Use of Chicory (Cichorium intybus L.). Sci Pharm. 2024;92(2):31 [Crossref]

14- Chen J, Wang H, Zhu J. Extract from Falcaria vulgaris loaded with exosomes for the treatment of hypertension in pregnant mice: In vitro and In vivo investigations. BME. 2024;:1 [Crossref]

15- Butnariu M, Fratantonio D, Herrera-Bravo J, Sukreet S, Martorell M, Ekaterina Robertovna G, Les F, López V, Kumar M, Pentea M, Sarac I, Becherescu A, Cruz-Martins N, Setzer W, Iriti M, Rasul Suleria H, Sharifi-Rad J. Plant-food-derived Bioactives in Managing Hypertension: From Current Findings to Upcoming Effective Pharmacotherapies. CTMC. 2023;23(8):589 [Crossref]

16- Landazuri P, Chamorro N, Cortes B. Medicinal Plants Used in the Management Hypertension. JAPLR. 2017;5(2) [Crossref]

17- Mphuthi D, Husaini D. Traditional medicinal plants used by hypertensive patients in Belize: a qualitative evaluation of beliefs and practices. Bull Natl Res Cent. 2022;46(1) [Crossref]

18- Nureye D, Tadege G, Dubale S, Kebebe D, Suleman S, Nguelefack-Mbuyo E. Medicinal plants administered to control hypertension in Ethiopia: ethnomedicine, pharmacology, nutraceutical, phytochemistry, toxicology, and policy perspectives. Front Cardiovasc Med. 2025;12 [Crossref]

19- Rajakumaran S, Christiya C R. Anti-proliferative effects of Euphorbia hirta L on the activity of cytotoxicity in bone cancer MG-63 cells. RJPT. 2021;:2221 [Crossref]

20- Vijayakumar S, Arulmozhi P, Rajalakshmi S, Mahadevan S, Parameswari N. A review of the taxonomy, ethno-botany and pharmacological activity of Atalantia monophylla L. Acta Ecologica Sinica. 2020;40(3):204 [Crossref]

21- Tamang S, Singh A, Bussmann R, Shukla V, Nautiyal M. Ethno-medicinal plants of tribal people: A case study in Pakyong subdivision of East Sikkim, India. Acta Ecologica Sinica. 2023;43(1):34 [Crossref]

22- Di Cerbo A, Carnevale G, Avallone R, Zavatti M, Corsi L. Protective Effects of Borago officinalis (Borago) on Cold Restraint Stress-Induced Gastric Ulcers in Rats: A Pilot Study. Front Vet Sci. 2020;7 [Crossref]

23- Duguluri S, S S. IN VITRO CYTOTOXICITY STUDIES ON ISOLATED AND PURIFIED COMPOUNDS FROM CHRYSOPOGON ZIZANIOIDES CHLOROFORM EXTRACT ON VERO AND HCT-116 CANCER CELL LINES. IJAR. 2021;:37 [Crossref]

24- Slama M, Slougui N, Benaissa A, Nekkaa A, Sellam F, Canabady‐Rochelle L. Borago Officinalis L.: A Review Oon Extraction, Phytochemical, and Pharmacological Activities. Chemistry & Biodiversity. 2024;21(5) [Crossref]

25- Ghazizadeh F, Khalili N. Hypertension Treatment in Central Iran with Medicinal Plants: A Review of Ethnobotanical Evidence from Iran. pbp. 2025;7(3):0 [Crossref]

26- Malik S, Odeyemi S, Pereira G, Freitas L, Abdul-Hamid H, Atabaki N, Makhzoum A, Almeida E, Dewar J, Abiri R. New insights into the biotechnology and therapeutic potential ofLippia alba(Mill.) N.E.Br. ex P. Wilson. Journal of Essential Oil Research. 2021;33(6):523 [Crossref]

27- IDM'HAND E, MSANDA F, CHERİFİ K. A review of Moroccan Medicinal Plants Used in the Treatment of Hypertension. 2022;6(1):48 [Crossref]

28- Idm'hand E, El-Ouazzani Y, Msanda F, Cherifi K. Ethnopharmacological review of medicinal plants used to manage hypertension in Morocco. 2022;14(2):202 [Crossref]

29- Ergül Bozkurt A. Traditional Usage of Some Natural Plant Taxa in Artvin/Tütüncüler Village of Türkiye. 2024;20(1):248 [Crossref]

30- Park J, Shin S, Bu Y, Choi H, Lee K. Vasorelaxant and Blood Pressure-Lowering Effects of Cnidium monnieri Fruit Ethanol Extract in Sprague Dawley and Spontaneously Hypertensive Rats. IJMS. 2024;25(8):4223 [Crossref]

31- Ray S, Saini M. Cure and prevention of cardiovascular diseases: herbs for heart. Clin Phytosci. 2021;7(1) [Crossref]

32- Silva M, Barbosa S, Silva D, Bezerra I, Alves Bezerra É, Coelho A, Pinheiro da Silva Morais I, Rezende-Júnior L, Carmo I, Lima-Neto J, Comerma-Steffensen S, Citó A, Arcanjo D, Zivkovic J. Bioactive Natural Products against Systemic Arterial Hypertension: A Past 20-Year Systematic and Prospective Review. Evidence-Based Complementary and Alternative Medicine. 2022;2022:1 [Crossref]

33- Ramachandran R, Alwi R, Mazaya M, Prem P, Kamaraj C, Maytasya S, Soleha M. Natural antihypertensive agents: innovative extraction techniques: Bioactive profiling and mechanistic pathways for therapeutic development. South African Journal of Botany. 2026;188:494 [Crossref]

34- Ko C, Chao J, Chen P, Su S, Maeda T, Lin C, Chiang H, Huang S. Ethnobotanical Survey on Skin Whitening Prescriptions of Traditional Chinese Medicine in Taiwan. Front Pharmacol. 2021;12 [Crossref]