eISSN: 2345-2781  



First published online: 20 Dec 2016
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. 2017;6(3):199-204.
doi: 10.15171/jrip.2017.38

Original Article

Comparative study of community acute kidney injury in young patients versus elderly patients in an internal medicine department in Abidjan (Côte d’Ivoire)

Kouamé Hubert Yao 1 * , Monlet Cyr Guei 2, Weu Melanie Tia 2, Serge Didier Konan 1, Séry Patrick Diopoh 1, Sindou Sanogo 1

1 Department of Nephrology and Internal Medicine, University Hospital of Treichville, Abidjan, Côte d’Ivoire
2 Department of Nephrology University Hospital of Yopougon, Abidjan, Côte d’Ivoire
*Corresponding author: Kouamé Hubert Yao, Email: yaohubert@yahoo.fr

Abstract

Introduction: Numerous studies have shown that the recovery of renal function was slower and less complete in the elderly patients than in adults.

Objectives: To compare the profile of acute kidney injury (AKI) of the young patients with that of the elderly patients.

Patients and Methods: This is a prospective study carried out during the period from January 2010 to December 2015 in the department of Nephrology-Internal Medicine of the University hospital of Treichville. The diagnosis of AKI was retained according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria.

Results: The mean age of patients was 26.8 ± 6 years in the young and 69.4 ± 7 years in the elderly. The proportion of males was 51.9% (55/106) in the young patients against 77.8% (84/108) in the elderly patients (P = 0.0001). The proportion of hypertension and diabetes in the elderly patients, respectively 30.6% and 36.1% was statistically higher than in the young patients (P = 0.001). However, human immunodeficiency virus (HIV) infection was more prevalent in the young patients (P = 0.0001). Anemia was observed in 84.9% in the young patients against 58.3% in the elderly patients (P = 0.001). It was severe in 34% among the young patients against 15.7% among the elderly patients (P = 0.002). The proportion of drug AKI was 17% in the young patients against 2.8% in the elderly patients (P = 0.0001). Malignant hypertension (P = 0.002) and urinary tract tumors (P = 0.001) were more observed in the elderly patients. Mortality was 31.1% in the young patients against 47.2% in the elderly patients (P = 0.011).

Conclusion: The etiologies are the same with different proportions, except malignant hypertension observed only in the elderly patients. Mortality is higher in the elderly patients.

Implication for health policy/practice/research/medical education:

In our study, we found that regardless of age, infection is the leading cause of acute kidney injury (AKI). Drug-induced AKI is more common in young adults. On the other hand, benign tumor of the urinary tract and malignant hypertension are more found in the elderly. In addition, mortality and non-recovery of renal function are higher in the elderly. The causes of death and the factors associated with mortality and non recovery of renal function differ in both groups.

Please cite this paper as: Yao KH, Guei MC, Tia WM, Konan SD, Diopoh SP, Sanogo S. Comparative study of community acute kidney injury in young patients versus elderly patients in an internal medicine department in Abidjan (Côte d’Ivoire). J Renal Inj Prev. 2017;6(3):199-204. DOI: 10.15171/jrip.2017.38.

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