Logo-jrip
ePublished: 01 Dec 2012
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

J Renal Inj Prev. 2012;1(1): 33-36.
doi: 10.12861/jrip.2012.12
PMID: 25340101
PMCID: PMC4205983
  Abstract View: 3448
  PDF Download: 1940

Case Report

Tuberous sclerosis, deep vein thrombosis and lack of C and S proteins: A case report

Seyed Seifollah Beladi-Mousavi 1, Abbasali Zeraati 2, Farzaneh Sharifipour 2*, Masih Naghibi 2, Farnaz Kalani 2, Sara Moussavinik 2, Marzieh Beladi-Mousavi 3

1 1Department of Internal Medicine, Faculty of Medicine, Jundishapour University of Medical Sciences, Ahvaz, Iran
2 Department of Nephrology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Chemistry, Behbahan Branch, Islamic Azad University, Behbahan, Iran
*Corresponding Author: *Corresponding author: Dr. Farzaneh Sharifipour, Department of Nephrology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Email: Sharifipourf@mums.ac.ir

Abstract

Introduction: Tuberous sclerosis, an autosomal dominant disorder, is characterized by hamartomas in different organs of body. Kidney involvement is quite common in this disorder and sometimes it is accompanied by adult polycystic kidney disease.Case: A 46-year-old woman who was being treated for adult polycystic kidney disease and systemic hypertension was admitted to this hospital because of acute lower limb edema. Color Doppler sonography study showed deep vein thrombosis of lower limbs and also left iliac vein. Despite the initiation of hourly heparin infusion, the patient involved by pulmonary emboli on the 2nd day of admission. Lab tests revealed protein C and S deficiency. The patient had already experienced episodes of pneumothorax too. Cutaneous lesions due to sebaceous adenoma were seen on her cheeks, nose and neck. She had also periungual fibroma suggestive of tuberous sclerosis.Conclusion: Although, according to our patient with both tuberous sclerosis and protein C and S deficiency, a significant relation between these two diseases, cannot confirmed, however, evaluation of other patients who have tuberous sclerosis can help to confirm or rule out this relation.

Implication for health policy/practice/research/medical education
Tuberous sclerosis, an autosomal dominant disorder, is characterized by hamartomas in different organs of body. Kidney involvement is quite common in this disorder and sometimes it is accompanied by adult polycystic kidney disease. Regarding the few number of patients with both tuberous sclerosis and protein C and S deficiency, a significant relation between these two, cannot be obviously found. Evaluation of the patients who have tuberous sclerosis can help to confirm or rule out this relation and its etiology.

Please cite this paper as: Beladi-Mousavi S, Zeraati A, Sharifipour F, Naghibi M, Kalani F, Moussavinik S, et al. Tuberous sclerosis, deep vein thrombosis and lack of C and S proteins: A case report. J Ren Inj Prev 2012; 1(1): 33-36.
First Name
Last Name
Email Address
Comments
Security code


Abstract View: 3449

Your browser does not support the canvas element.


PDF Download: 1940

Your browser does not support the canvas element.