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ePublished: 10 Oct 2013
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J Renal Inj Prev. 2013;2(4): 119-121.
doi: 10.12861/jrip.2013.38
PMID: 25340147
PMCID: PMC4206029
  Abstract View: 3375
  PDF Download: 2412

Mini-Review

Erythropoietin; a review on current knowledge and new concepts

Mohamad-Reza Tamadon 1, Seyed Seifollah Beladi-Mousavi 2*

1 Department of Internal Medicine, Semnan University of Medical Sciences, Semnan, Iran
2 Department of Internal Medicine, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran
*Corresponding Author: *Corresponding author: Dr. Seyed Seifollah Beladi-Mousavi, Department of Nephrology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. , Email: Beladimusavi@yahoo.com

Abstract

Chronic kidney disease (CKD) is a worldwide health problem. However, despite to new routes of dialysis, mortality and morbidity is high. One of the most common symptom of CKD is anemia, especially is more obvious in stages 3 and 4. In this review, we compared the effects of erythropoietin and anemia correction on kidney function (GFR) by investigating in various studies. Despite extensive studies in this category, still we do not sure about the effects of erythropoietin and anemia correction on the glomerular filtration rate.

Implication for health policy/practice/research/medical education: It seems that the treatment of anemia by recombinant human erythropoietin in chronic kidney disease, when it accompanied by control of metabolic complications, can improve anemia, however more human studies needs to find the effect of erythropoietin on kidney function.

Please cite this paper as: Tamadon MR, Beladi-Mousavi SS. Erythropoietin; a review on current knowledge and new concepts. J Ren Inj Prev 2013; 2(4): 119-121. DOI: 10.12861/jrip.2013.38
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