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ePublished: 01 Jul 2014
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J Renal Inj Prev. 2014;3(3): 79-82.
doi: 10.12861/jrip.2014.23
PMID: 25340174
PMCID: PMC4206056
  Abstract View: 3313
  PDF Download: 1633

Case Report

Neuroblastoma accompanied by hyperaldosteronism

Kaan Gulleroglu 1*, Umut Bayrakci 1, Sibel Tulgar Kinik 2, Nihal Uslu 3, Alev Ok Atilgan 4, Faik Sarialioglu 5, Esra Baskin 1

1 Department of Pediatric Nephrology, Baskent University, Ankara, Turkey
2 Department of Pediatric Endocrinology, Baskent University, Ankara, Turkey
3 Department of Radiology, Baskent University, Ankara, Turkey
4 Department of Pathology, Baskent University, Ankara, Turkey
5 Department of Pediatric Oncology, Baskent University, Ankara, Turkey
*Corresponding Author: *Corresponding author: Dr. Kaan Gulleroglu, Baskent University Pediatric Nephrology Department. 54. Cadde No: 72/3. Bahcelievler-Cankaya. Ankara, Turkey. , Email: kaangulleroglu@yahoo.com

Abstract

Background: Tumors known derived from kidneys which take place in secondary hyperaldosteronism etiology are juxtaglomerular cell tumor and Wilms’ tumor. Neuroblastoma presenting with hyperaldosteronism is rare.Case: A 15-month-old girl who had been having diarrhea and fever for 2 weeks presented with a 3 day history of bilious vomiting, metabolic acidosis and severe hypokalemia. She was referred to our hospital with the pre-diagnosis of unknown manifest hypertension etiology, diarrhea, and paralytic ileus after having therapy-resistant hypokalemia and severe resistant acidosis. On her examination after being admitted to our clinic, she was weak, unwell and lethargic with a blood pressure of 140/93 mmHg. Due to the hypertension and severe hypokalemia, the patient was considered to be hyperaldosteronism. Serum aldosterone level, plasma renin activity and cortisol level were elevated. Radiologic findings were compatible with neuroblastoma. The patient underwent an abdominal surgery and the mass excision. The histopathological examination was proved neuroblastoma.Conclusion: Hyperaldosteronism can be presented by unexpected atypical forms as in our patient

Implication for health policy/practice/research/medical education: Physicians should be aware that hyperaldosteronism can be presented by unexpected atypical forms as in our patient. To sum up, imaging techniques and pathological diagnosis have to be considered to determine the etiology of hyperaldosteronism. Please cite this paper as: Gulleroglu K, Bayrakci U, Tulgar Kinik S, Uslu N, Ok Atilgan A, Sarialioglu F, Baskin E. Neuroblastoma accompanied by hyperaldosteronism. J Renal Inj Prev 2014; 3(3): 79-82. DOI: 10.12861/jrip.2014.23
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