Abstract
            Introduction: Evidence suggests that end-stage renal disease (ESRD) significantly affects general  health in the patients, causing their general health to be poorer compared to the general population.  The Roy adaptation model (RAM) is the best one for ESRD patients.  
  Objectives: The present study aimed to determine the effect of a RAM-based care plan on general  health in hemodialysis patients.  
  Patients and Methods: This randomized controlled clinical trial conducted on 60 hemodialysis  patients in Iran. The data collected using a demographic questionnaire and the general health  questionnaire-28 (GHQ-28). In the intervention group, the Roy assessment form was completed  and the RAM-based care plan was then trained in four group sessions over 4 weeks. Individual  sessions were also held if required and patients followed-up for 2 weeks. The control group received  only routine care. At the end of the follow-up, general health was re-assessed in the patients. The  findings were analysed using t test, the chi-square test and the McNemar test.  
  Results: Despite observing no significant differences between the two groups in terms of general  health levels before the intervention (P=0.530), the difference was significant after the intervention  (P=0.028), since the mean score of general health decreased by 4.07 in the intervention group  compared to before the intervention (P=0.003). The intervention significantly affected the  subscales of somatic symptoms (P=0.013), anxiety and insomnia (P=0.006), social dysfunction  (P=0.016) and depression (P=0.031).  
  Conclusion: The findings suggested the positive effects of using the RAM on general health in  hemodialysis patients. The RAM is therefore recommended that be used as a holistic care approach  to improving general health in these patients.