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Submitted: 20 Aug 2019
Accepted: 16 Dec 2019
ePublished: 10 Jan 2020
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J Renal Inj Prev. 2020;9(2): e16.
doi: 10.34172/jrip.2020.16

Scopus ID: 85085752864
  Abstract View: 1986
  PDF Download: 1036

Original

Relationship between biochemical indices in hemodialysis patients and mortality; survival analysis

Mojde Jahanbani Far 1 ORCID logo, Majid Mirmohammadkhani 2, Tahereh Jalali 3, Amin Izadi 1 ORCID logo, Maliheh Yarmohamadi 4* ORCID logo

1 Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran
2 Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran
3 Community Medicine, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Internal Medicine, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran
*Corresponding Author: *Corresponding author: Maliheh Yarmohamadi, Email: , Email: malihehyarmohammadi@yahoo.com

Abstract

Introduction: People with chronic kidney disease (CKD) undergoing hemodialysis pay high costs and suffer from complications like premature death.

Objectives: This study was conducted to determine the relationship of various blood parameters in hemodialysis with premature death.

Patients and Methods: In this cross-sectional study, 90 hemodialysis patients were enrolled using consensus sampling method. Demographic characteristics were recorded. Additionally, serum level of ferritin and biochemical parameters were assessed. The log-rank test for survival probability and Cox proportional-hazards model were applied to examine the correlation between assessed factors and the risk of premature death.

Results: The results of log-rank test showed that only coronary artery disease (CAD) and serum ferritin have a role in predicting survival probability, since the survival rate of the people with and without CAD was about 25 months (with a confidence interval of 37.60 - 12.36) and 46 months (with a confidence interval of 51.63-40.36) (P = 0.041) respectively.

Conclusion: It seems that both serum ferritin levels and cardiovascular diseases are effective factors to predict premature death in hemodialysis patients.


Implication for health policy/practice/research/medical education:

In a study on 90 hemodialysis patients we found a significant relationship between serum ferritin level and coronary artery disease with premature death in hemodialysis patients.

Please cite this paper as: Jahanbani Far M, Mirmohammadkhani M, Jalali T, Izadi A, Yarmohamadi M. Relationship between biochemical indices in hemodialysis patients and mortality; survival analysis. J Renal Inj Prev. 2020; 9(2): e16. doi: 10.15171/ jrip.2020.16.

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