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Submitted: 23 Dec 2021
Accepted: 15 Feb 2022
ePublished: 04 Mar 2022
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J Renal Inj Prev. 2022;11(2): e31972.
doi: 10.34172/jrip.2022.31972

Scopus ID: 85130413351
  Abstract View: 1368
  PDF Download: 937

Case Report

Hemolytic uremic syndrome following COVID-19; a case report

Elham Emami 1 ORCID logo, Samaneh Safari 2*, Pedram Javanmard 3 ORCID logo

1 Pediatric Nephrology Research Center (PNRC), Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Clinical Research Development Unit, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Division of Endocrinology, Diabetes, and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA
*Corresponding Author: *Corresponding author: Samaneh Safari, Email: , Email: samane.safari.med@gmail.com

Abstract

High incidence of thromboembolic diseases in patients with coronavirus disease 2019 (COVID-19) have been reported that can affect several organs ranging from cutaneous thrombosis to pulmonary embolism, stroke, coronary thrombosis or kidney infarction. There are two proposed mechanisms for these phenomena, disseminated intravascular coagulation (DIC) and endotheliopathy. We report a case of 11-year-old girl presented to the emergency department with generalized tonic colonic seizure with upward gaze which was repeated in emergency room. Respiratory distress and loss of consciousness happened which led to her intubation. Due to increased serum creatinine levels and impaired consciousness which was associated with thrombocytopenia and hemolysis, she underwent plasmapheresis three times by the diagnosis of hemolytic uremic syndrome. Additionally, antihypertensive therapy was conducted. The patient’s condition improved and was discharged with good circumstances. Two weeks later the patient returned with thromboembolism that happened in the distal part of her left hand which underwent fasciotomy and thrombectomy.

Implication for health policy/practice/research/medical education:

In this case report, we showed hemolytic uremic syndrome and thromboembolism in the brain led to seizure following COVID-19 development.

Please cite this paper as: Emami E, Safari S, Javanmard P. Hemolytic uremic syndrome following COVID-19; a case report. J Renal Inj Prev. 2022; 11(2): 31972. doi: 10.34172/jrip.2022.31972.

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