Submitted: 19 Jun 2023
Accepted: 25 Aug 2023
ePublished: 23 Sep 2023
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J Renal Inj Prev. 2023;12(4): e32226.
doi: 10.34172/jrip.2023.32226

Scopus ID: 85174744027
  Abstract View: 605
  PDF Download: 521


Pregnancy in immunoglobulin A nephropathy patients; an updated review

Elham Saffarieh 1 ORCID logo, Seyedeh Reyhaneh Yousefi Sharemi 2* ORCID logo

1 Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran
2 Department of Obstetrics and Gynecology, Kurdistan University of Medical Sciences, Sanandaj, Iran
*Corresponding Author: Seyedeh Reyhaneh Yousefi Sharmi, Email: Yousefi805@yahoo.com


Immunoglobulin A nephropathy (IgAN) is found as the most frequent primary glomerulonephritis worldwide, predominantly affecting the younger population. The peak incidence of this disease occurs between the second and third decades of life, thereby making pregnancy a significant concern for women diagnosed with IgAN. Extensive studies have demonstrated that pregnancy itself does not inherently pose a specific risk for the deterioration of kidney function in individuals with IgAN who are in the initial stages of chronic kidney disease. However, it is important to note that IgAN elevates the risk of preeclampsia, a condition that is a pivotal risk factor contributing to unfavorable outcomes during pregnancy. Consequently, healthcare providers should be attentive to the potential complications of preeclampsia in pregnant women with IgAN, as its presence holds substantial implications for maternal and fetal well-being.

Implication for health policy/practice/research/medical education:

Immunoglobulin A nephropathy (IgAN) is a common primary glomerulonephritis, especially in young people. While pregnancy does not necessarily worsen kidney function in early IgAN stages, the risk of preeclampsia is heightened due to IgAN, potentially leading to adverse pregnancy outcomes.

Please cite this paper as: Saffarieh E, Yousefi Sharemi SR. Pregnancy in immunoglobulin A nephropathy patients; an updated review. J Renal Inj Prev. 2023; 12(4): e32226. doi: 10.34172/jrip.2023.32226.

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