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Submitted: 14 Sep 2024
Revision: 17 Dec 2024
Accepted: 10 Jan 2025
ePublished: 06 Feb 2025
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J Renal Inj Prev. 2025;14(2): e38396.
doi: 10.34172/jrip.2025.38396
  Abstract View: 63
  PDF Download: 34

Review Article

Preferred radiological modalities in the diagnosis and management of kidney and urinary tract stones; a systematic review

Ranin Haghighi 1 ORCID logo, Jalal Rezaei 2 ORCID logo, Fatemeh Khaleghi 3 ORCID logo, Mohammad Hamidi Madani 4 ORCID logo, Hussein Soleimantabar 5 ORCID logo, Mahsa Norouzi 6 ORCID logo, Mojtaba Karbalaee 7 ORCID logo, Zahra Askari 8 ORCID logo, Roozbeh Roohinezhad 9 ORCID logo, Rasoul Jafari Arismani 10* ORCID logo

1 Department of Urology, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnord, Iran
2 Department of Critical Care Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Radiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4 Urology and Nephrology Research Center, Department of Urology, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5 Department of Radiology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Department of Radiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
7 Department of Radiology, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran
8 Department of Medical Emergencies, Sirjan School of Medical Sciences, Sirjan, Iran
9 Department of Urology, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran
10 Department of Urologic Surgery, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
*Corresponding Author: Rasoul Jafari Arismani, Email: Ra.jafari009@yahoo.com

Abstract

Introduction: Kidney and urinary tract stones are a common health concern, with a rising global incidence and significant impact on patient quality of life. Accurate diagnosis and effective management of these stones rely heavily on radiological imaging modalities. This systematic review aimed to synthesize the existing literature on preferred radiological modalities for diagnosing and managing kidney and urinary tract stones, focusing on their diagnostic accuracy, clinical efficacy, and impact on treatment outcomes.

Methods: This systematic review was conducted based on PRISMA guidelines to evaluate preferred radiological modalities for diagnosing and managing kidney and urinary tract stones. A comprehensive literature search across multiple databases, including PubMed, Embase, Cochrane Library, Scopus, and Google Scholar, was conducted up to July 2024, using a comprehensive set of MeSH keywords. Quality assessment was performed using the STROBE checklist, with medium and high-quality studies considered acceptable. Data extraction by two independent reviewers captured essential information, with discrepancies resolved through discussion or consultation with a third reviewer.

Results: The results of 12 included studies in this review indicated that, while CT scans are the most accurate imaging modality for diagnosing kidney and urinary tract stones, ultrasound presents a viable alternative due to its lower radiation exposure. Most studies reported ultrasound sensitivities above 55% and specificities over 95% compared to CT, although some studies noted significantly lower sensitivities. Additionally, X-ray imaging showed limitations, with sensitivities of only 46% to 57%, particularly for smaller stones.

Conclusion: This study highlights that while CT scans are the gold standard for diagnosing kidney and urinary tract stones due to their accuracy, ultrasound presents a valuable alternative as an initial diagnostic tool, primarily because of its lower radiation exposure, which enhances patient safety, especially for those needing repeated imaging. Furthermore, the limitations of X-ray imaging in detecting smaller stones caution against its exclusive use. The review also emphasizes the importance of balancing diagnostic accuracy with safety when considering high-dose versus low-dose CT scans.

Registration: This study has been compiled based on the PRISMA checklist, and its protocol was registered on the PROSPERO (ID: CRD42024579547) and Research Registry (UIN: reviewregistry1873) websites.



Implication for health policy/practice/research/medical education:

The findings from this systematic review have significant implications for clinical practice in diagnosing and managing kidney and urinary tract stones. While CT scans are the most accurate imaging modality, the results suggest that the ultrasound may serve as a suitable initial diagnostic tool, particularly given its lower radiation exposure, making it a safer option for patients, especially in cases requiring repeated imaging. The variability in sensitivity reported for the ultrasound highlights the importance of considering specific clinical contexts and patient characteristics when selecting imaging modalities. Furthermore, the limitations of X-ray imaging, particularly in detecting smaller stones, underscore the necessity for clinicians to be cautious when relying solely on this method for diagnosis. The comparison between high-dose and low-dose CT scans also emphasizes the need for a balanced approach that maximizes diagnostic accuracy while minimizing radiation exposure. Ultimately, these results advocate for a tailored imaging strategy that prioritizes patient safety without compromising diagnostic effectiveness..

Please cite this paper as: Haghighi R, Rezaei J, Khaleghi F, Hamidi Madani M, Soleimantabar H, Norouzi M, Karbalaee M, Askari Z, Roohinezhad R, Jafari Arismani R. Preferred radiological modalities in the diagnosis and management of kidney and urinary tract stones; a systematic review. J Renal Inj Prev. 2025; 14(2): e38396. doi: 10.34172/jrip.2025.38396.

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