Hossein Emad Momtaz
*1 Division of Pediatric Nephrology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract
Renal involvement in thalassemia major is an important concern of both pediatric
nephrologists and pediatric hematologists. Both glomerular and tubular injury may precede
overt kidney dysfunction in these patients and may be due to deleterious effects of hemolysis,
iron overload and iron chelator therapy. Here we present a case of thalassemia major with
acute kidney injury with findings in favor of hemolytic uremic syndrome and consequent
posterior reversible encephalopathy syndrome who needed multiple sessions of hemodialysis
and finally recovered uneventfully
Implication for health policy/practice/research/medical education:
Patients with β thalassemia major are at risk of renal damage due to multiple mechanisms. Frequent monitoring of kidney
function and attention to level of iron overload, dose and duration of chelator therapy is highly recommended in this group of
patients.
Please cite this paper as: Momtaz HE. Acute kidney injury and posterior reversible encephalopathy syndrome in a boy with β
thalassemia major. J Renal Inj Prev. 2018;7(3):215-217. doi: 10.15171/jrip.2018.50.