Abstract
Introduction: Kidney transplantation restores many of the disorders accompanying endstage renal disease (ESRD). However, hypophosphatemia is common complication after
renal transplantation. High levels of fibroblast growth factor 23 (FGF23) and parathyroid
hormone (PTH) are two suspected factors determining the hypophosphatemia after kidney
transplantation.
Objectives: This observational prospective study was carried out to clarify the role of
mentioned factors in hypophosphatemia after kidney transplantation.
Patients and Methods: Living donor kidney transplant recipients which admitted to the
ward of the renal transplantation, enrolled to the study. Parameters of bone and mineral
metabolism including FGF23 and intact PTH levels were assessed.
Results: High FGF23 level before transplantation was related to lower phosphate levels at 3rd
month after transplantation. PTH levels showed no relationship with hypophosphatemia
after kidney transplantation.
Conclusion: High levels of FGF23 in ESRD patients undergoing kidney transplantation is an
important determinant of hypophosphatemia in long-term follow up.