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Submitted: 09 May 2019
Accepted: 10 Sep 2019
ePublished: 06 Oct 2019
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J Renal Inj Prev. 2019;8(4): 306-310.
doi: 10.15171/jrip.2019.56

Scopus ID: 85076308257
  Abstract View: 2414
  PDF Download: 1060

Original Article

Study of risk factors for development of urinary bladder cancer in patients in Urmia; a single-center study by logit regression approach

Rasool Gharaaghaji 1 ORCID logo, Yasamin Pouladi 2 ORCID logo, Ali Tehranchi 2* ORCID logo

1 Department of Biostatistics and Epidemiology, Urmia University of Medical Sciences, Urmia, Iran
2 Urology and Nephrology Research Center, Urmia University of Medical Sciences, Urmia, Iran
*Corresponding Author: *Corresponding author: Ali Tehranchi, Email:, Email: A.tehranchiii132@gmail.com

Abstract

Introduction: Urinary bladder cancer is the most common genitourinary system malignancy in humans. Objectives: Due to the high prevalence of urinary bladder cancer, having enough knowledge about urinary bladder cancer risk factors can assist in prevention and early recognition of this malignancy.

Patients and Methods: In this study case-control, 109 individuals with urinary bladder tumor (as a case group) and 200 individuals without any neoplastic history aged >40 years (as a control group) were included (2016-2017). The data were collected using patients’ files, their pathology reports and also a checklist. The data were analyzed using SPSS version 20, and logistic regression test was applied to investigate the binary outcome. A P value less than 0.05 was considered significant.

Results: The results showed, a significant relationship between smoking (P<0.001), having high risk occupation (P<0.001), low water intake (P<0.001) and pickle consumption (P<0.001) with urinary bladder cancer.

Conclusion: Smoking is a strong risk factor for urinary bladder cancer. Our study showed smoking and other occupational carcinogens are the main causes of urinary bladder cancers. Thus preventing and controlling these risk factors are important for health schedules. 


Implication for health policy/practice/research/medical education:

According to the results of our study, it seems that the risk factors of cigarette smoking, male gender, high-risk occupation, the use of pickles and low-intake of water are associated with urinary bladder cancer. It should be noted that in our population, the risk of urinary bladder cancer was increased with the increase of smoking and occupational hazards as risk factors.

Please cite this paper as: Gharaaghaji R, Pouladi Y, Tehranchi A. Study of risk factors for development of urinary bladder cancer in patients in Urmia; a single-center study by logit regression approach. J Renal Inj Prev. 2019; 8(4): 306-310. doi: 10.15171/ jrip.2019.56.

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