Afshin Safaei Asl
1*, Peyman Dadashzadeh
21 Division of Nephrology, Department of Pediatrics, Guilan University of Medical Sciences, Rasht, Iran
2 Resident of Pediatrics , Guilan University of Medical Sciences, Rasht, Iran
Abstract
Paraquat and diquat are classified as bipyridyl compounds not only leads to acute organ damage, but also to a variety of complications. Patients with severe paraquat-induced poisoning may succumb to multiple organ failure involving the circulatory and respiratory systems. Deliberate self-poisoning with paraquat continues to be a major public health concern in many developing countries. At present there is no specific antidote to paraquat poisoning, hence the need to more focus on prevention and in cases of poisoning aggressive decontamination to prevent further absorption. This article presented a 12-year-old male with acute kidney injury following the ingestion of paraquat in suicidal attempt and serves to explore the complications associated with paraquat poisoning and current recommended treatment
Implication for health policy/practice/research/medical education:
Paraquat is a broad spectrum liquid herbicide associated with both accidental and intentional ingestion. Toxicity is usually seen following ingestion, and may range from mild to fulminant with the latter commonly proving fatal. In addition to intense local irritation of the mouth, oropharynx and esophagus, multiple organ (cardiac, respiratory, hepatic and renal) failure may occur, although pulmonary features predominate and are the usual cause of death. This article presented a 12-year-old male with acute kidney injury following the ingestion of paraquat in suicidal attempt that admitted and discussed the probable ways for effective management of the patient.
Please cite this paper as: Safaei Asl A, Dadashzadeh P. Acute kidney injury in patients with paraquat intoxication; a case report and review of the literature. J Renal Inj Prev. 2016;5(4):203-206. DOI: 10.15171/jrip.2016.43